Ketamine hcl 500mg/10ml

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Ketamine is used by medical practitioners and veterinarians as an anaesthetic. It’s sometimes used illegally by people to get high.

Ketamine is a dissociative drug, which means it acts on different chemicals in the brain to produce visual and auditory distortion, and a detachment from reality.

When it’s sold illegally, ketamine usually comes as a white or off-white powder. It can also be made into pills, or dissolved in a liquid.

Clinical trials and studies are assessing ketamine as a treatment for depression. Early indications show good results.

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What is Ketamine?

Ketamine (brand name: Ketalar) is a dissociative injected anesthetic (blocks sensory perception) that has been available by prescription in the U.S. since the 1970s for human and veterinary uses. Esketamine (Spravato), the S-enantiomer of racemic ketamine, was approved in 2019 for treatment-resistant depression and is approved for use in depressed patients with acute suicidal ideation or behavior. Ketaset is the brand name of a surgical anesthesia used by veterinarians

Dissociative drugs can lead to distortion of sights, colors, sounds, self, and one’s environment. Ketamine is available in a clear liquid or off-white powder form for intravenous injection or as a nasal spray. Examples of other dissociative drugs include phencyclidine (PCP) and dextromethorphan (DXM).

In the U.S., This drug is classified as a schedule III drug under the DEA Controlled Substances Act; however, it is not classified as an opioid (narcotic) or barbiturate.

What are the uses of ketamine?

Ketamine is a medication that is used to induce loss of consciousness, or anesthesia. It can produce relaxation and relieve pain in humans and animals.

It is a class III scheduled drug and is approved for use in hospitals and other medical settings as an anesthetic.

However, it is also a commonly abused “recreational” drug, due to its hallucinogenic, tranquilizing and dissociative effects.

Controversy has arisen about using ketamine “off-label” to treat depression. Off-label uses of drugs are uses that are not approved by the the United States, (U.S.) Food and Drug Administration (FDA).

This is safe to use in controlled, medical practice, but it has abuse potential. Used outside the approved limits, its adverse mental and physical health effects can be hazardous. Prolonged use can lead to tolerance and psychological addiction.

How does ketamine work?

It’s not entirely clear how this drug works. Because it exerts an antidepressant effect through a new mechanism, ketamine may be able to help people successfully manage depression when other treatments have not worked.

One likely target for this is NMDA receptors in the brain. By binding to these receptors, It appears to increase the amount of a neurotransmitter called glutamate in the spaces between neurons. Glutamate then activates connections in another receptor, called the AMPA receptor. Together, the initial blockade of NMDA receptors and activation of AMPA receptors lead to the release of other molecules that help neurons communicate with each other along new pathways. Known as synaptogenesis, this process likely affects mood, thought patterns, and cognition.

What dosage will be administered during my infusion?

When you come in for your first trial of infusion, the starting dose will be very low. This is because some people (less than 1%) are very sensitive to even lower doses. The doses are reviewed every 24-hours and slowly increased until the desired pain relief is obtained, or side effects begin to occur. If you have had an infusion previously, your treating specialist will decide the dosage based upon your previous results and experience.

Are there any side effects?

Due to the slow and steady protocol that we use, side effects are generally predictable and are at the milder end of what ketamine can cause. A feeling of slight sedation, perhaps even some grogginess is common as the dose increases into the range where most people get some benefit. Other side effects caused from high doses of ketamine can include forgetfulness, disorientation and hallucinations. This goes away (as do all the ketamine related side-effects) within a few hours of ceasing the infusion.

Effects

Ketamine use can have a wide variety of adverse effects, including:

  • drowsiness
  • changes in perceptions of color or sound
  • hallucinations, confusion, and delirium
  • dissociation from body or identity
  • agitation
  • difficulty thinking or learning
  • nausea
  • dilated pupils and changes in eyesight
  • inability to control eye movements
  • involuntary muscle movements and muscle stiffness
  • slurred speech
  • numbness
  • amnesia
  • slow heart beat
  • behavioral changes
  • increased pressure in the eyes and brain
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    Justin

    Always prompt dispatch and receipt.
    The support agent, Steve, is always polite and helpful.
    I recommend this site.

    August 10, 2021

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